Genes for SE are found in these alleles: HLA-DRB1*04:01,*04:04, *04:05, (HLA-DR4), HLA-DRB1*01:01 (HLA-DR1), HLA-DRB1*10:01 (HLA-DR10) [1], and are present in about two-thirds of seropositive RA patients [2]. Here, HLA-DRB1 is linked to rheumatoid arthritis.