Univariate cause-specific Cox regression analysis found age (p = 0.006), tumor size (p = 0.006), surgery period (p = 0.034), EOR (p = 0.001), brain invasion (p = 0.017), sheeting (p = 0.039), MC (p = 0.005) and Ki-67 (p = 0.032) as a risk factor for AM progression. Here, MKI67 is linked to neoplasm.