CD163 and diabetes mellitus: In addition, several studies have highlighted the significant impact of neutrophil-to-lymphocyte ratio and basophil counts on recurrence, with higher neutrophil-to-lymphocyte ratio and basophil granulocyte counts correlating with poorer prognosis.16,17 Furthermore, research has documented that patients with type 2 diabetes mellitus, positive pre-operative urine cytology, and high CD163+ macrophage infiltration have an increased likelihood of recurrence and a worse prognosis.18-20