The intervention alleviated oocyte reduction and exhibited anti‐apoptotic effects. It reduced sex hormone disturbances in PCOS, improved oxidative stress markers, and decreased elevated TNF‐α levels. The treatment restored PI3K/AKT/mTOR levels, alleviated insulin resistance, improved β‐cell function, and preserved islet integrity. It also normalized sex hormone levels. This evidence concerns the gene TNF and polycystic ovary syndrome.