When stratified by variant type, carriers of GBA mutations exhibited a similar elevation in dementia risk (RR = 1.82, 95% CI: 1.49–2.23, p < 0.00001), and carriers of GBA polymorphisms also demonstrated a heightened risk (RR = 1.82, 95% CI: 1.26–2.61, p = 0.001). The gene discussed is GBA1; the disease is dementia.