For GBA polymorphisms, subgroup analysis by dementia diagnostic criteria showed an RR of 2.12 (95% CI: 1.59–2.83, p < 0.00001) for DSM-IV criteria and an RR of 1.82 (95% CI: 1.26–2.61, p = 0.001, I2 = 76%) for MDS criteria. This evidence concerns the gene GBA1 and dementia.