Furthermore, this meta-analysis acknowledges the existence of GBA variants beyond N370S, L444P, and E326K, including other Gaucher disease-related pathogenic mutations (e.g., D409H, R463C, RecNciI complex allele) and other polymorphisms (e.g., E388K, R120W, IVS10+1G>T), which may contribute to PD and PDD risk in specific populations. Here, GBA1 is linked to Gaucher disease.