Based on the limited background of m6A methylation of circRNA in NSCLC, we undertook a comprehensive investigation into the latent relationship between circ_0060927 and its regulation through m6A methylation, specifically mediated by the methyltransferase METTL14, and how this interplay influences the progression of NSCLC. Here, METTL14 is linked to non-small cell lung carcinoma.