UM-SCC-047 and UPCI-SCC-090 cells treated with JQ1 demonstrated a relative downregulation in the expression of TP63, FOSL1, TP73, TEAD4, E2F1, TP53, PPARG, and E2F3—TFs primarily enriched in tumor-specific domains (Figure 2C). Here, TP63 is linked to neoplasm.