Furthermore, in the analysis of iron metabolites and sepsis, there were 2 SNPs in SI, 86 SNPs in SF, 4 SNPs in STF, 4 SNPs in TFRC, and 29 SNPs in TSP; and SF was a risk factor of sepsis (OR = 3.079, 95%CI: 1.420~6.679, P = 0.004). This evidence concerns the gene TFRC and Sepsis.