The distinct profile in gut‐derived γδ T cells from PLWH is largely due to high IFN‐γ expression, as seen in Figure 2A. It is possible that gut IL‐17+ γδ T cells are also impacted by HIV infection; however, no significant difference was observed when comparing IL‐17‐expressing γδ T cells in the gut of PLWH vs. PWOH (Figure 2B). The gene discussed is IFNG; the disease is HIV infectious disease.