The capacity to produce ET was not restricted to PMN-MDSC from infected patients; indeed, PMN-MDSC from G-CSF mobilized healthy individuals were able to produce ET when stimulated by COVID-19 PRP, indicating that PRP from COVID-19 patients delivers signals inducing ET formation by PMN-MDSC from both COVID-19 patients and HD. Here, CSF3 is linked to Huntington disease.