VEGFA and diabetic macular edema: The Vision-Related Quality of Life in Patients with Diabetic Macular Edema Treated with Intravitreal Aflibercept (AQUA) study reported that aflibercept treatment led to sustained improvements in NEI VFQ-25 scores over one year of follow-up, confirming the impact of anti-VEGF agents on patient-centered measures of visual function [24].