Another rare situation found in association with lupus erythematosus is Rowell syndrome (RS), originally explained by Rowell et al. in 1963 as the co-existence of lupus erythematosus (systemic or cutaneous) with erythema multiforme-like lesions with a distinctive immunologic pattern, including positive antinuclear antibody (ANA) and anti-Ro/SSA or anti-La/SSB antibodies [6,7]. This evidence concerns the gene BTG3 and lupus erythematosus.