SREBF1 and Disorder of lipid metabolism: It was also found that uric acid induces lipid metabolism disorders through lysophosphatidylcholine acyltransferase 3 (LPCAT3)-mediated activation of sterol regulatory element binding protein 1c (SREBP-1c) and inhibition of phosphorylation signaling transducer and activator of transcription 3 (p-STAT3 (Liu et al., 2020).