AKT1 and esophageal squamous cell carcinoma: Curcumin suppressed AKT phosphorylation by enhancing miR-532-3p expression, thereby decreasing the activation of the AKT pathway. In conclusion, curcumin serves as a strong inhibitor of ESCC proliferation, mediated through the modulation of the circNRIP1/miR-532-3p/AKT pathway