Recently, curcumin has been shown to affect RNA methylation (m6A) by regulating writer (METTL3/METTL14), eraser (ALKBH5/FTO), and reader (YTHDF1/2) proteins, thereby altering mRNA stability and translation in cancer, inflammatory, and metabolic contexts (Sun et al., 2024; Li et al., 2025). The gene discussed is YTHDF1; the disease is cancer.