Nevertheless, it is important to mention, that global histone acetylation is a dynamic process regulated by both histone acetylation and histone deacetylation (Wang and Luo, 2025), therefore future studies are needed to determine the exact histone-acetylation levels and perform gene-specific methylation and histone-acetylation analyses to evaluate the direct relationship between the altered placental epigenetic pattern and ABC transporter expression changes in schizophrenia. Here, ABCG2 is linked to schizophrenia.