CD47 and neoplasm: However, combined PD-L1 and CD47 blockade did not significantly improve upon either NDV-αCD47 or NDV-sPD1 treatment alone, and similar increases in tumor volumes were observed (Figures 5B and 5C), although one mouse in the combined CD47 and PD-L1 blockade group experienced complete remission (CR) (Figure 5B).