The frequency of underdeveloped gonads and incomplete germline development phenotypes increased by simultaneous knockdown of Smed-METTL3 and Smed-METTL14 (METTL3;METTL14(RNAi)), resulting in 85 % of the ovaries lacking oocytes (Fig. 4D) and 71 % of samples with azoospermia (Fig. 4H). Here, METTL3 is linked to Azoospermia.