However, studies have shown that Segatella abundance is increased in rheumatoid arthritis (RA), and its potential role in the pathogenesis of RA may involve stimulating helper T cell (Th) 17 populations and inducing the production of Th17 cell-related cytokines (IL-6 and IL-23) (Korzeniowska et al., 2024). Here, IL6 is linked to rheumatoid arthritis.