HTi pDCs also showed elevated RUBCNL (autophagy),59BCL11A (enhances Bcl-2 and pDC development),60 and PRXL2A (redox regulation),61 reinforcing the notion of autophagy activation and mitochondrial stress in response to infection (Figures S7A and S7B; Table S9). The gene discussed is PRXL2A; the disease is infection.