Knowing that ZMIZ1 is expressed in endometrial cells, that ZMIZ1 impacts signaling of transcription factors associated with endometrial function (TP53, NOTCH1, ESR1, SMAD), and that the ZMIZ1 gene super enhancer interacts with ESR1, we examined whether ZMIZ1 might be associated with diseases of the endometrium. The gene discussed is TP53; the disease is endometrial disorder.