Immune infiltration analysis showed that tumors with higher USP5 expression contained fewer CD8+ T cells and macrophages (Figure 1I and Supplemental Figure 2, B and C), as well as fewer CXCL9hi macrophages in NPC, HNSC, and SKCM (Figure 1J and Supplemental Figure 2D). This evidence concerns the gene CD8A and nasopharyngeal carcinoma.