DKK1 and polycystic ovary syndrome: Our analysis revealed that when serum DKK1 concentrations were within tertiles 2 and 3, the odds ratios (ORs) for the presence of PCOS and IR were 7.36 [95% confidence interval (CI), 2.90; 18.69] and 18.01 [95% CI, 7.08; 45.77] for PCOS and 2.95 [95% CI, 1.44; 6.04] and 4.95 [95% CI, 2.36; 10.36] for IR, respectively (Figure 3D,E).