The association between insulin therapy receivers and in‐hospital death was stronger among CKD patients for MIMIC (OR, 1.66 [95% CI, 1.41–1.69], p < 0.01, p for interaction = 0.01) and TJHFIT (OR, 2.94 [95% CI, 1.86–4.75], p < 0.01, p for interaction = 0.01). Here, INS is linked to chronic kidney disease.