This analysis revealed that zinc-alpha-2-glycoprotein(AZGP1) and myosin regulatory light chain 1 (ORM2) were consistently upregulated in the T2D group acrossmost studies, whereas apolipoprotein A-I (APOA1)was generally downregulated in the T2D group (Figure E, Supporting Information 3). The gene discussed is ORM2; the disease is type 2 diabetes mellitus.