SMC2 and lung adenocarcinoma: Furthermore, we conducted univariate and multivariate Cox regression analyses to assess the correlation between these genes and clinical factors, such as age, gender, clinical stage, T stage, N stage, and M stage, identifying SMC2, NCAPG, NCAPH, NCAPD2, and NCAPG2 as independent risk factors for lung adenocarcinoma (Table S3).