This builds on previous findings, including our own, showing that CSF levels of the pericyte marker sPDGFRβ16, 17, 18, 19, 20, 22 and CSF levels of endothelial injury, including VEGF‐A, ICAM‐1, VCAM‐1,13 ANGPT2,20 and cadherin,29 correlate with CSF t‐tau and p‐tau in early AD. The gene discussed is ANGPT2; the disease is Alzheimer disease.