On 28 days after vaccination, the seropositive rates of anti-pertussis antibodies in the co-purified DTaP increased to 85.47% (200/234, 95% CI: 80.38–89.41) for PT and 97.44% (228/234, 95% CI: 94.52-98.82) for FHA. Here, F2 is linked to pertussis.