NLRP3 and asthma: Another NLRP3 inhibitor is OLT1177 ® (dapansutrile) was experimented on OVA-induced asthma mouse, house dust mite induced asthma model and synthetic analogue of viral RNA Poly(I: C)-induced exacerbation of OVA asthma, and showed to reduce airway inflammation and lower eosinophils and Neutrophils counts in bronchoalveolar lavage fluid (BALF) in all models, in addition to finding comparable results in both oral and injections [68].