RT-qPCR and WB validation also validated that CDC73, PSMC2, SOCS3, and ETV4 were substantially upregulated in GBM cells (SHG-44, U87, and U251) than that in control astrocytes group (SVG p12), whereas PLK2 and LMO7 were substantially downregulated in GBM cells than that in control microglia (Fig. 7D and E and S4, P < 0.05). The gene discussed is SOCS3; the disease is glioblastoma.