Elevated GC levels suppressed Gad1 expression (7 and 14 DIV) and Pvalb expression (21 DIV), and at 7 DIV, blockade of GRs with mifepristone elevated expression of both Gad1 and Pvalb. These 2 GABAergic interneuron genes, both of which show reduced expression levels in schizophrenia, are clearly sensitive to elevated GC levels. Here, GAD1 is linked to schizophrenia.