The scope of research is broader, not only covering the role of GGT in antioxidative stress but also comprehensively analyzing the diversity of the GGT gene family from the perspective of genomics and transcriptomics, as well as its expression pattern, mechanism, and prognostic significance in multiple tumor types, such as hepatocellular carcinoma, colorectal carcinoma, gastric carcinoma, and breast carcinoma. This evidence concerns the gene GGTLC3 and hepatocellular carcinoma.