PGGT1B and hepatocellular carcinoma: Moreover, Weidong Shen experimentally verified that the positive rate of the GGT I mRNA B subtype combined with AFP mRNA in diagnosing hepatocellular carcinoma could reach 98%, the positive rate of small hepatocellular carcinoma could reach 95.2%, and the combined monitoring of the GGT I mRNA subtype and AFP mRNA could aid in the early diagnosis of hepatocellular carcinoma [80].