GGT6 and nonpapillary renal cell carcinoma: GGT6, a component of metabolism related prognostic profile (MRPS), is expressed at low levels in renal clear cell carcinoma tissues compared to normal tissues, and samples with high expression levels of GGT6 showed a significant increase in the overall survival (OS) of patients compared to samples with low expression levels. Zhou, R et al. found that knockdown of GGT6 significantly promotes renal cancer cell proliferation, migration and invasion ability, GGT6 may have an inhibitory effect on the occurrence and development of ccRCC and is expected to be a therapeutic target of ccRcc [65].