Daubeuf suggested that GGT mRNA in hepatocellular carcinoma cells is predominantly of subtype B. Sheen suggested that the GGT I mRNA subtype B is related to the serum AFP level in tumor foci, degree of differentiation of the tumor cells, residual postoperative infiltration, postoperative infiltration of the tumor, postoperative recurrence, and postoperative survival, and monitoring GGT I mRNA is an important indicator for predicting whether recurrence occurs after surgery. The gene discussed is PGGT1B; the disease is neoplasm.