Extensive research has revealed that METTL14 functions as a central mediator in modulating inflammatory responses across various diseases, such as coronary artery disease [21, 22], psoriasis [23, 24], rheumatoid arthritis [25], glomerulonephritis [26], colitis [27], and ankylosing spondylitis [28]. The gene discussed is METTL14; the disease is rheumatoid arthritis.