In prostate cancer (PCa), NAT10 enhances the stability of high mobility group AT-hook 1 (HMGA1) and Keratin 8 (KRT8) by acetylating their mRNAs, hence accelerating cell cycle progression to improve cell proliferation and enhancing EMT progression to facilitate cell migration, respectively [18]. The gene discussed is HMGA1; the disease is posterior cortical atrophy.