The acetylation of RNA, specifically ac4C, has been shown to play a significant role in the regulation of gene expression in various types of cancers [60]; NAT10, the sole acetyltransferase that catalyzes the conversion of cytosine to N4-acetylcytidine, also contributes to the regulation of cancer initiation and metastasis [60, 63]. This evidence concerns the gene NAT10 and cancer.