Additionally, patients with elevated IgE were significantly less likely to have controlled asthma based on ACT scores (OR = 0.2, 95% CI: 0.1–0.3, p < 0.001) and were also less likely to have fewer acute care service visits (OR = 0.3, 95% CI: 0.2–0.4, p < 0.001). The gene discussed is IGHE; the disease is asthma.