Even after controlling for the potential confounding factors, including age, sex, SBP, Killip classification I-II, previous MI, previous HF, TnI, NT-proBNP, Hs-CRP levels, LVEF, primary PCI, thrombolytic therapy, triple-vessel disease, LM culprit, stent implantation, IABP, complete coronary revascularization, ACEI or ARB, and dual antiplatelet medication, a one-unit Gensini score increase was found to be associated with 1.2% increases in all-cause mortality, thus demonstrating an independent and positive correlation between Gensini scores and the clinically relevant endpoints. This evidence concerns the gene NPPB and hydrops fetalis.