Similarly, tissue-resident memory CD8+ T cells expressed LIGHT, a proinflammatory cytokine that stimulates T cells and activates NF-κB to increase innate immune signaling and/or trigger apoptosis (Skeate et al, 2020), which was sensed only in early tumors by all tumor cell and some immune cell subclusters. Here, NFKB1 is linked to neoplasm.