NEK7 and Hepatic fibrosis: We observed a similar protective effect of NEK7 on CDAHFD-induced liver fibrosis, as evidenced by decreased levels of fibrosis-related genes and proteins (Fig. 8b-h), decreased fiber deposition (Fig. 8i-l), and mitigated pathological injury and oxidative damage (Fig. 8m-o), although hepatic lipid accumulation (TG, triglyceride) was not affected (Fig. 8p).