The results showed that the expression of TRIM25 was correlated with the clinical stage, tumor size, and distant metastasis of breast cancer patients, but not with the age and lymph node metastasis, while the combined expression of TRIM25 and BRD7 correlated with the clinical stage, tumor size, lymph node metastasis, and distant metastasis of breast cancer patients (Table 3). This evidence concerns the gene BRD7 and metastatic malignant neoplasm in the lymph nodes.