One of the more active and well-studied transcripts is that of HERV-K and its subgroup HML-2, and in a study by Agoni et al., they detected transcription products of the HERV-K (HML-2) coding chain in the LNCaP, DU145, PC3, and VCaP prostate cancer cell lines. The gene discussed is CLEC10A; the disease is prostate cancer.