HLA-C and neoplasm: Concurrently, DAMPs and cytokines promote antigen presentation via MHC molecules, eliciting potent cytotoxic T lymphocyte (CTL) responses [13,14], and recruit lymphocytes to the tumor site for coordinated killing of infected tumor cells while simultaneously eliminating tumor cells in non-directly infected metastatic lesions, thereby inducing the “abscopal effect” (Fig. 1b) [27,54].