Additionally, the SMPP and RMPP groups exhibited higher levels of C-reactive protein (CRP), white blood cells (WBC), platelets, neutrophil-to-lymphocyte ratio (NLR), lactate dehydrogenase (LDH), and D-dimer, and a higher incidence of pleural effusion (P < 0.05). The gene discussed is CRP; the disease is Pleural effusion.