EPG5 and Vici syndrome: Although there is the possibility that the presence of pancreatic involvement in our Vici syndrome patients may be coincidental, there are several lines of evidence to suggest that the association is indeed genuine: Pancreatitis has been previously reported in one other EPG5-mutated patient [18] (in a case series describing an attenuated form of Vici syndrome), strengthening our hypothesis of a potential causative link between EPG5 deficiency and pancreatic involvement.