MBs can also be targeted specifically to areas of interest through the attachment of targeting ligands, such as antibodies, to the shell, which shows promise for the detection of specific vascular biomarkers of disease (e.g. Vascular Endothelial Growth Factor Receptor 2,VEGFR-2, for the detection of new vasculature associated with fast growing cancers) [[17], [18], [19]]. This evidence concerns the gene KDR and cancer.