Additionally, the fraction of a total of 14 immune cells showed a significant difference between C1 and C2 subtypes (both p < 0.05; Figure 3e), such as CD8 T cells, activated NK cells, and M2 macrophages, as well as immune score, tumor purity, and stroma score (both p < 0.001; Figure 3f). Here, CD8A is linked to neoplasm.