For example, they developed a NIR-II strategy for accuratebreastcancer (BC) subtyping and 3D visualization using fluorescent Au24Pr1 NCs. Three differentmonoclonal antibodies targeting estrogen receptor (ER), progesteronereceptor (PR), and human epidermal growth factor receptor 2 (HER2)construct the Au24Pr1 probes to identify BCsvia NIR-II light-sheet microscopy (LSM). This evidence concerns the gene ESR1 and breast cancer.