SOD2 and fatty liver disease: KLB (Klotho-beta), which has been linked to increased inflammation and fibrosis in obese patients with fatty liver (46); SOD2 (Superoxide Dismutase 2), linked to the management of oxidative stress at the mitochondrial level, its variants can influence cell damage in the liver; and LPIN1 (Lipin 1) which plays a role in lipid metabolism and its variants have been associated with the disease (47).