ASPECTS, Alberta Stroke Program early CT score; ATBI, atherothrombotic brain infarction; BA, basilar artery; CT, computed tomography; DWI, diffusion-weighted imaging; ESUS, embolic stroke of undetermined source; ICA, internal carotid artery; ICH, intracranial hemorrhage; MRI, magnetic resonance imaging; mRS, modified Rankin Scale; MT, mechanical thrombectomy; mTICI, modified thrombolysis in cerebral infarction; NIHSS, National Institutes of Health Stroke Scale; PC, posterior circulation; tPA, tissue plasminogen activator; VA, vertebral artery. The gene discussed is PLAT; the disease is brain infarction.