Among the variants, two nonsynonymous single-nucleotide variants, KRAS (exon 2:c.G35T:p.G12V, allele frequency 0.714) and PIK3CA (exon 2:c.G263A:p.R88Q, allele frequency 0.42), have been previously reported as pathogenic somatic mutations in cancers. Here, PIK3CA is linked to cancer.