Biallelic KCTD7 variants are a known cause of autosomal recessive progressive myoclonic epilepsy type 3 (PME3), characterized by early-onset drug-resistant epilepsy, myoclonic and generalized seizures, progressive cognitive decline, and ataxia (Gil-Nagel et al., 2019). The gene discussed is KCTD7; the disease is cerebellar ataxia.