AKT1 and atherosclerosis: KEGG pathway analysis identified 142 significantly enriched pathways (p < 0.05), as illustrated in Figure 6E. These findings suggest that licorice exerts its antiaging effects primarily through the PI3K-Akt pathway, as well as pathways related to lipid metabolism, atherosclerosis, cancer, the AGE-RAGE pathway in diabetic complications, MAPK, and the IL-17 pathway.